The medical benefits of IV Therapy
LET’S PUT SOME SCIENCE TO WORK
We’ve compiled a wealth of information as to how IV therapy can help you and what goes into it. Take a look and, as always, if you still have any questions, feel free to contact us.
We’ve compiled a wealth of information as to how IV therapy can help you and what goes into it. Take a look and, as always, if you still have any questions, feel free to contact us.
Water is critical for some of your body’s most important functions. It helps to nourish cells, flush toxins out of organs, and protect the eyes, ears and nose by keeping them moist. In fact, water makes up approximately 60% of the average adult human body.
This leads to a variety of symptoms, including headaches, muscle fatigue, and loss of coordination. Even small amounts of water loss may hinder cognitive ability, athletic performance, and mood.
Oral hydration is limited by the time it takes the water that is consumed to be emptied from the stomach and absorbed by the intestine. This process is particularly slow on an empty stomach.
Which depends on sufficient electrolyte levels. And this, you guessed it, is tightly linked to water absorption in the intestines.
IV infusions offer a more efficient means to hydration because infusions bypass the gastrointestinal (GI) tract and enter directly into the bloodstream, delivering much faster hydration along with a balanced complement of electrolytes and nutrients.
The World Health Organization lists IV hydration as an essential medicine, based on the effectiveness and efficiency of this method and the importance of hydration to life and wellness. These infusions have become the gold-standard for providing hydration in hospitals.
Ascend's infusions produce unparalleled benefits. Enriched with bountiful nutrients and strategically formulated to provide maximum absorption rates, these infusions harness the benefits of IV hydration while simultaneously conferring other health benefits as well.
We’re down with being a little nerdy here. Our ingredients, sourced and handled with great care, provide countless ways to enrich, repair and boost your body. And just so you know we did our homework, here’s the notes that match the numbers.
Ascorbic acid (vitamin C) has a range of cosmetic benefits. For one, it is important for the synthesis of collagen, which is abundant in healthy skin and connective tissue, as well as in bones.1 Vitamin C can therefore protect against natural skin aging and accelerate wound and bone healing,1–3 making it an attractive resource for plastic surgeons. Vitamin C is commonly used in dermal fillers for the treatment of wrinkles and aging skin.
Vitamin C is also a powerful antioxidant and immune system enhancer that plays a role in fighting infections and in iron absorption and utilization.4–6 Several studies have demonstrated specific health benefits of vitamin C, including its ability to reduce the risk of heart disease, treat lung fibrosis, and improve arterial stiffness and endothelial function.7–10
Natural Food Sources: citrus fruits, berries, peppers, broccoli, potatoes, tomatoes, leafy greens Taking vitamin C can speed recovery and reduce the duration of cold symptoms.4,11 Recovery time is even more important for individuals under physical stress, including competitive athletes, marathon runners, and other highly active individuals.
Body requirements for vitamin C may increase under certain conditions, such as during illness, smoking, or cigarette smoke exposure. Use of certain drugs like oral contraceptives, and physical, emotional, or environmental stress can deplete the body of vitamin C and increase the need for this vitamin.
A healthy dose of Vitamin C in your system before and after drinking alcohol may prevent or reduce the severity of hangovers by stimulating hepatic metabolism of alcohol.
Biotin (vitamin B7) is an essential nutrient that improves energy by enabling the metabolism of fats and carbohydrates and helping to regulate blood sugar levels.12,13Biotin can be found in a number of beauty products because of its positive health effects on hair, skin, and nails. Indeed, biotin deficiency is associated with hair loss, brittle nails, and skin imperfections.14,15
Natural Food Sources: egg yolks, liver, meat, fish, seeds, nuts, sweet potatoes, spinach, broccoli
Cobalamin (vitamin B12) is important for the maintenance of normal brain functioning. A vitamin B12 deficiency can lead to severe neurological disorders such as a loss of sensation, dementia, and stroke, which, unlike other vitamin B deficiencies, may not be reversible.16,17 Vitamin B12 may, however, be used to treat brain abnormalities that are reversible.18
Vitamin B12 is also involved in DNA synthesis, fat metabolism, and the production and proliferation of red blood cells.19 A vitamin B12 deficiency can therefore lead to anemia.20
Natural Food Sources: beef, fish, poultry, eggs, milk
Based on the finding that vitamin B12 deficiency is higher than anticipated in the United States and is associated with adverse symptoms like fatigue, weakness, constipation, loss of appetite, and neurological and balance problems, the federal government has suggested in its Dietary Guidelines for Americans that people older than age 50 take supplements as a way to ensure adequate vitamin B12 intake.21
Niacin (vitamin B3) is necessary for the proper functioning of the digestive and nervous systems and skin, and is involved in converting carbohydrates and fat into energy. Niacin has long been used in the treatment of coronary heart disease, the skin disease Pellagra, age-related macular degeneration, and high cholesterol, with research demonstrating that niacin can boost levels of “good” cholesterol and lower harmful triglycerides.22,23 There is also evidence that niacin provides other cardiovascular benefits including reducing artery hardening and decreasing the risk of recurrent heart attacks.
Niacin is also associated with several skin benefits. It increases the production of ceramide, an important lipid that strengthens skin by retaining moisture and boosting skin hydration.24 In addition, it offers a unique mechanism of protection against UV-induced cell damage to protect skin from the effects of sun damage.25
Natural Food Sources: beef, fish, poultry, eggs
Niacin may prevent Langerhans cell depletion even with prolonged exposure to sun. Langerhans cells, the skin’s immune cells, are important for protecting and repairing skin from infections and abnormal cell development. Unfortunately, they are susceptible to sun damage and migrate away from the skin when exposed to the sun.
Dexpanthenol (vitamin B5) contributes to wound healing.26 It also forms coenzyme A, which is the main carrier of carbon molecules in a cell.27 Coenzyme A is important for the synthesis of lipids, cholesterol, and the neurotransmitter acetylcholine, which helps muscles to contract.
Natural Food Sources: beef, eggs, milk, peanuts, vegetables
Pyridoxine (vitamin B6) is important for the synthesis of brain chemicals known as neurotransmitters, as well as for elevating red blood cell levels.28,29 Vitamin B6 deficiency can cause anemia and symptoms of muscle weakness, dermatitis, mouth sores, fatigue, anxiety, and confusion.30,31
Natural Food Sources: beef, potatoes, whole grains, bananas, avocados
Good to Know: Women who experience stress responses such as hyperventilation or panic attacks are more likely (than those who do not endure these responses) to have low levels of vitamin B6 and iron. 30
Riboflavin (vitamin B2) plays a vital role in maintaining the body’s energy supply through its involvement in fat, protein, and carbohydrate metabolism. It supports health through its antioxidant properties and is important for maintaining healthy red blood cell levels and promoting healthy eyes, nerves, muscles, and skin.32–34
Natural Food Sources: dairy, eggs, spinach, mushrooms, almonds, fish, beef, poultry
According to the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society, riboflavin is likely effective for the prevention of migraines and so endorses the use of this ingredient in migraine sufferers.35
Thiamine (vitamin B1) is necessary for healthy nerve and brain cells and promotes wound healing.36 It has also been shown to be involved in glucose metabolism, DNA and RNA synthesis, and energy production.37,38
Natural Food Sources: whole grains, dairy, peanuts, beans, seeds, liver
Calcium is best known for its important role in building and maintaining healthy bones and teeth. It is, however, critical to a number of other key body structures and functions as well, including cardiac muscle contraction, blood vessel contraction and expansion, blood clotting, hormone and enzyme secretion, and nervous system signaling.39–41 Several clinical trials have demonstrated that increasing dietary calcium helps to lower blood pressure and to reduce the risk of hypertension.
Natural Food Sources: dairy, salmon, tofu, sesame, legumes, dark leafy greense
Copper is important for energy production, iron transport, and the synthesis of blood cells and melanin. It assists with the crosslinking of collagen and elastin, making this mineral important for maintaining healthy skin and providing structural support to bone and connective tissue throughout the body.42,43 Copper also helps prevent damage associated with oxygen-mediated free radicals and helps sustain the integrity of some of the brain’s key neurotransmitter systems.44
Natural Food Sources: green leafy vegetables, seeds, nuts, mushrooms, shellfish, liver, legumes
Copper can benefit those with inflammatory diseases such as osteoarthritis and rheumatoid arthritis.
Good to Know: Copper is an essential trace mineral that is the third most abundant mineral in the body (after iron and zinc). Copper is found in skeletal muscle and skin, but the highest concentrations are found in the brain and liver.
Magnesium is essential for regulating hundreds of biochemical processes and several physiological systems that uphold metabolic and cardiovascular health.45,46 Magnesium promotes healthy functioning of muscles and nerves and regulates blood glucose levels.47
It also plays an important role in building bones through its relationship with calcium and vitamin D and supports a healthy immune system. Magnesium deficiency can lead to insomnia, low energy, and weakness.
Natural Food Sources: spinach, beans, peas, whole grains, nuts (especially almonds)
Good to Know: Numerous studies are currently underway to investigate the impact of magnesium intake on bone health, cardiovascular health and blood pressure regulation, as well as its impact on the risk of stroke, type 2 diabetes, and migraines.
Good to Know: If you have stomach or intestinal problems, type 2 diabetes, or long-term alcohol abuse, or if you’re an older adult, you’re more likely to have sub-optimal blood levels of magnesium. Average magnesium intakes in the United States have significantly declined over the last few generations, and National Health and Nutrition Examination Survey (NHANES) data from 2000 show that 68% of adults in the U.S. consume less than the recommended amount of magnesium.48
Manganese is an essential nutrient that assists in the formation of bones and connective tissue, the synthesis of sex hormones, the regulation of blood glucose, and the metabolism of fat and carbohydrates.49–51
Natural Food Sources: dark green leafy vegetables, salts (e.g. Himalayan and Celtic sea salt)
Good to Know: Manganese serves as a component of the major free-radical neutralizer, manganese superoxide dismutase, in the energy-generating mitochondria of most body cells. Mitochondria perform cellular respiration; taking in nutrients from the cell, breaking them down, and converting them into energy.
Selenium is important for reproductive function, thyroid hormone synthesis and metabolism, DNA synthesis, and protecting the body from infection and damage caused by free radicals.52 It also plays a significant role in preventing chronic diseases, including certain forms of cancer.53,54 Observational studies have found a decreased risk for coronary heart disease with high selenium concentrations.55 These benefits are likely linked to the ability of selenium to prevent lipid oxidation, which can reduce inflammation and prevent platelets from aggregating.
Natural Food Sources: salmon, eggs, dairy, beef
Selenium supplementation may forestall age-related decline in cognitive function through selenium’s antioxidant activities.56 Indeed, serum selenium concentration declines with age and may lead to declines in neuropsychologic functions among aging people.57
Zinc is an essential trace element that serves numerous biological functions throughout the body. It aids in wound healing, supports skin health, keeps senses sharp, protects vision by preventing retinal cell damage, and is vital for a well-functioning immune system.58–61 Zinc is also involved in the proper metabolism of testosterone. Low zinc is a known culprit in cases of hypogonadism and impotence.62
Natural Food Sources: oysters, beef, poultry, vegetables, mushrooms, legumes, seeds, nuts, whole grains, dairy, dark chocolate
Good to Know: Despite its importance, many adults do not get enough zinc.63,64 High levels of alcohol consumption can result in a zinc deficiency, and certain medications can reduce zinc levels, including ACE inhibitors, thiazide diuretics, and stomach acid reducers.
Arginine is an amino acid that is best known as a growth hormone releaser. It also stimulates insulin secretion, T-cell defense, muscle development, and body fat burning.65,66 Additionally, arginine is the biological precursor of nitric oxide, an important vasodilator and regulator of blood pressure and flow,67 which acts as a signaling molecule to start and maintain blood engorgement of sexual organs.
Natural Food Sources: red meat, fish, poultry, wheat germ, grains, nuts and seeds, dairy products
Good to Know: Due to the purported benefits of nitric oxide and early positive studies, doctors sometimes prescribe arginine supplements to treat erectile dysfunction.
BCAA (Branched Chain Amino Acids) refers to the three structurally related amino acids leucine, isoleucine, and valine, well known for their roles in building and maintaining lean body mass. Leucine facilitates muscle protein synthesis while isoleucine induces glucose uptake into cells. Valine assists in protein metabolism and supports healthy insulin functioning and stem cell renewal. BCAA ingestion can increase leucine in tissues and stimulate the mTOR pathway in muscles.69
Natural Food Sources: chicken, fish, eggs, beans, lentils, nuts, soy
Good to Know: In one study, people who consumed a drink with 5.6 grams of BCAAs after their resistance workout had a 22% greater increase in muscle protein synthesis compared to those who consumed a placebo drink.70,71
Carnitine is a nonessential amino acid that the body produces primarily from glutamine. It plays an important role in fatty acid metabolism and blood glucose regulation and appears particularly beneficial for brain health.72–74
Natural Food Sources: beef, fish, poultry, dairy
Good to Know: Recent research indicates that maintaining sufficient levels of the amino acid L-carnitine may improve cardiac patients’ health.75
Good to Know: Carnitine has received substantial media attention in bodybuilding circles because optimal use may lead to a decrease in body fat percentage and an increase in energy.
Citrulline is one of the three dietary amino acids in the urea cycle, alongside arginine and ornithine. It is the biological precursor to arginine, an amino acid that is an important vasodilator and regulator of blood pressure and flow and also stimulates nitric oxide production. Citrulline has been observed to increase growth hormone concentrations, but this effect may depend on physical exercise.76,77
Natural Food Sources: watermelon, onions, garlic, legumes, liver, salmon, beef, nuts, dark chocolate
Good to Know:Citrulline is necessary for detoxifying the liver from the waste product ammonia.78 It also helps reduce potentially harmful lactic acid and ammonia in muscle tissues.
Good to Know: A study in the medical journal Urology found that citrulline supplementation may be an effective and natural way to treat mild to moderate erectile dysfunction by increasing the production of nitric oxide.79
Glutamine is an amino acid necessary for synthesizing protein.80 It is the most abundant amino acid in human tissue and plasma and has multiple biological roles . Glutamine is a very effective nutrient for the intestinal and immune systems, as the cells of these systems use glutamine as the preferred fuel source rather than glucose.81,82
Natural Food Sources: beef, chicken, fish, dairy, eggs, beans, beets, rice, corn, tofu, cabbage, fermented foods such as miso
Good to Know: Supplemental glutamine may improve nutritional management and augment recovery of the seriously ill.83 Indeed, the biological need for glutamine increases in certain contexts, such as with disease or cachexia.
Lysine is an essential amino acid that serves as a building block for proteins in the body. Because the body cannot make it on its own, lysine must be consumed through the diet or supplementation. This amino acid revitalizes the body by combatting fatigue and overtraining. It also increases calcium absorption while maintaining proper nitrogen balance to promote the healthy execution of vital bodily functions.84,85
Natural Food Sources: eggs, meat, soy, beans, peas, cheese, certain fish such as cod and sardines
Lysine seems to be a good oral supplement to combat symptoms of herpes simplex labialis, or “cold sores,” caused by the herpes simplex virus.86 It has been shown to reduce the frequency and severity of cold-sores and to accelerate their healing time.87
Ornithine is an amino acid that helps in recovery from physical fatigue, protects the liver, and helps the immune system to function properly.66,88–91 It is also key in the production of proline, glutamic acid and citrulline, each of which serves other important functions in the body.
Natural Food Sources: meat (especially turkey breast), fish, dairy, eggs
Ornithine may enhance performance during prolonged exercise that lasts 45 minutes or more.
Alpha-lipoic acid (ALA) is a nutrient that can control blood sugar levels, thereby combatting diabetes. Clinical evidence suggests it may improve insulin sensitivity and blood sugar control in people with type 2 diabetes, reduce symptoms of diabetic peripheral neuropathy, and enhance weight loss when dieting.92,93
ALA may also be beneficial in preventing vascular disease, inflammation, and hypertension and in fighting the aging process.94 It is associated with reductions in age-related cognitive decline as well as with a slower progression of cognitive decline in those with Alzheimer’s disease.95–97
Natural Food Sources: found in low amounts in spinach, broccoli, yams, potatoes, yeast, tomatoes, brussels sprouts, carrots, beets, rice bran
Good to Know: ALA is able to pass the blood-brain barrier and is putatively used for detoxification of mercury attached to the brain cells.
Good to Know: Because it can reverse signs of aging resulting from oxidative damage, ALA is often found in anti-aging products.
Good to Know: Intravenous treatment with ALA has been found to reduce symptoms of nerve pain caused by damage to the peripheral nerves in diabetes.98
CoQ10 (coenzyme Q10; ubiquinol) plays an important role in energy production and is critical for cells with high energy demands.99 CoQ10 also acts as an antioxidant, which allows it to benefit those with inflammation and cardiovascular disease.100
Natural Food Sources: organ meats such as animal liver and heart, beef, pork, chicken, fatty fish such as tuna CoQ10 may boost energy and speed recovery of exercise-related muscle exhaustion and damage.101
Oral absorption of CoQ10 is very poor, so the majority of oral supplements are excreted unabsorbed by the intestines. To maximize oral absorption, CoQ10 supplements are best taken with fatty foods. IV infusion bypasses the gastrointestinal system and ensures 100% transport directly into the blood stream for distribution to the various tissues of the body and brain.102
Good to Know: CoQ10 and its activated form, ubiquinol, are among the most popular supplements in the U.S. They may be useful in treating congestive heart failure and in preventing migraine headaches.75,103
Glutathione is a tripeptide that can be found in virtually every cell of the human body. Glutathione is the body’s most potent antioxidant, referred to as the “master antioxidant” because of its ability to enhance the effectiveness of other antioxidants, which scavenge and neutralize free radicals.104,105 The highest concentration of glutathione is found in the liver, where it is critical in the body’s detoxification process. It protects the brain and liver from damage by drugs, alcohol, and other noxious substances.106,107 Glutathione deficiency and dysregulation are increasingly recognized as risk factors for neurodegenerative disease,108and glutathione can confer benefits to those with asthma, as well as to those with several forms of cancer.109,110
Natural Food Sources: sulfur-rich proteins such as beef, fish, poultry
Exercise elevates glutathione levels and thereby helps boost the immune system, as well as detoxify and enhance the body’s own antioxidant defenses.
Vitamin C plays a vital role in maintaining glutathione levels by converting oxidized glutathione back to its active form.111 For this reason, vitamin C may help increase glutathione levels in your body, as demonstrated in some clinical studies.112
MIC (methionine, inositol, choline) is a combination of vitamins and nutrients, each with distinct weight-loss properties. These elements work together synergistically to release and burn stored body fat. The combined effect of these three lipotropic agents has garnered much commercial and popular interest in recent years.
L-methionine may protect the liver, and is a principle supplier of sulfur, which protects the kidneys and serves a host of other functions. Sulfur also prevents bladder irritation and disorders of the hair, skin, and nails and helps to reduce cholesterol.113,114
Inositol aids in fat metabolism and decreases blood sugar levels.115 It also facilitates communication between brain cells by improving the effectiveness of neurotransmitters. Inositol may improve fertility, as it has been proven to increase sperm count and motility,116 as well as increase the overall quality of oocytes and embryos.117
Choline aids in fat and cholesterol metabolism and prevents excessive fat build up in the liver. It is also needed for good nerve conduction throughout the central nervous system because it is a precursor to the neurotransmitter acetylcholine. In addition, choline helps with gallbladder regulation, liver function, and the formation of lecithin, a key lipid. Choline has been used to mitigate the effects of Parkinsonism and tardive dyskinesia.118,119
Natural Food Sources: Methionine: eggs, meat, fish, sesame seeds, Brazil nuts, dairy, soy
Inositol: citrus fruits, cantaloupe, beans, grains, nuts Choline: eggs, liver, peanuts, poultry, fish, dairy, spinach, beets, shellfish
Choline may help improve short-term memory and attention in older adults127 and cognition in people with mild to moderate Alzheimer’s disease.128
Good to Know: As it presents a relevant role in ensuring oocyte fertility, inositol has been studied for its use in the management of polycystic ovary syndrome (PCOS).120 In PCOS, the administration of inositol has led to symptom remission, reductions in male hormone secretion,121 cholesterol level regulation,122 and more efficient fat breakdown..123
Good to Know: Choline insufficiency can lead to the accumulation of fat in the liver because it lowers the level of the molecule needed to transport fat away from the liver. 124 Choline deficiency can lead to liver damage and is associated with increased incidence of liver cancer.125,126